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A HIV coinfected patient with BV.Leiahmaniasis is given Amphotericin B has had seizures which is now rare after giving him the medicine again after a gap of about ten days on completion of 14 days But still suffers from severe headache,Vision issues, hearing issues,nausea and vomiting,loss of appetite.But ART is with

L
Lianminthang Thomte
Posted Under Others, on 20 January 2025

L
Lianminthang Thomte
Posted Under Others, on 20 January 2025
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Dr. Bhavya GuptaExpert

Hello Mr Thomte,

Thank you for reaching out. Based on the details shared, the patient is dealing with HIV coinfection and visceral leishmaniasis, for which Amphotericin B is being administered. The reported symptoms—seizures (rare), severe headache, vision and hearing issues, nausea, vomiting, and loss of appetite—warrant a detailed assessment, as these could be related to the underlying conditions, treatment side effects, or other complications.

Immediate Steps and Suggested Treatment Options

  1. Clinical Assessment and Consultation

    • Neurological Examination and consultation with Neurologist: To assess the cause of seizures, headaches, and vision/hearing issues.
    • Fundoscopy and Imaging: If headaches and vision changes persist, evaluate for papilledema or intracranial pressure.
    • Infectious Disease Specialist: To optimize HIV and leishmaniasis treatment and manage co-infections.

  2. Laboratory Tests

    • Monitor kidney function (serum creatinine, urea).
    • Check electrolytes (potassium, magnesium, calcium).
    • Perform a complete blood count and liver function tests.

  3. Medication Adjustment

    • Reassess the dosing schedule of Amphotericin B.
    • Consider anti-emetics for nausea/vomiting and appropriate medications for headaches and appetite stimulation.

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