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Hodgkin's and Non Hodgkin's Lymphoma Survival Rate

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Medically Reviewed by Dr. Aman Priya Khanna
Written by Sangeeta Sharma, last updated on 11 August 2023| min read
Hodgkin's and Non Hodgkin's Lymphoma Survival Rate

Quick Summary

  • Lymphomas are a group of blood cancers, and the two main types are Hodgkin's lymphoma and Non-Hodgkin's lymphoma.
  • Knowing the survival rates of these diseases is vital for those affected.
  • Patients can gain insights into their potential outcomes and make informed decisions about their healthcare.

Lymphomas are a group of blood cancers, and the two main types are Hodgkin's lymphoma and Non-Hodgkin's lymphoma. Knowing the survival rates of these diseases is vital for those affected.

Patients can gain insights into their potential outcomes and make informed decisions about their healthcare. This blog will discuss the prognosis and survival rates of Hodgkin's and Non-Hodgkin's lymphoma, providing information for patients and their families.

What is Hodgkin's Lymphoma?

Hodgkin lymphoma, formerly called Hodgkin disease, refers to blood cancers that primarily arise in the lymphatic system. These are acquired genetic conditions, meaning they are not present at birth but occur due to mutations in specific cells. 

Although Hodgkin lymphomas are not very common, they are the most frequent cancer affecting young adults. Fortunately, advancements in treatment have led to increased survival rates, allowing people to live longer after undergoing therapy.

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What is Non-Hodgkin's Lymphoma?

Non-Hodgkin's lymphoma (NHL) is a type of cancer that affects the lymphatic system, an essential part of the body's immune defence. It develops when tumours originate from specific white blood cells called lymphocytes.

NHL is more prevalent than Hodgkin's lymphoma, another form of lymphoma.

The primary distinction between Hodgkin's lymphoma and NHL lies in the presence of a unique cell called the Reed-Sternberg cell, found exclusively in Hodgkin's lymphoma. The treatment approaches for Hodgkin's lymphoma and NHL are also quite distinct.

Survival Rate of Hodgkin's Lymphoma

Hodgkin's lymphoma has a relatively high survival rate, with around 86% of patients surviving five years or more after diagnosis. The five-year survival rate indicates the percentage of patients still alive five years after diagnosis.

The survival rate can vary based on the stage at which the cancer is diagnosed. If detected in the early stages (Stage I or II), the chances of successful treatment and long-term survival are even higher. 

Advances in medical technology, early detection, and improved treatment options have increased survival rates for Hodgkin's lymphoma.

According to the American Cancer Society, the survival rates for different stages of Hodgkin's lymphoma are as follows: 

  1. Localised: This is stage 1 of Hodgkin lymphoma and is restricted to one lymphoid organ, one lymph node area, or one organ outside the lymph system. The 5-year survival rate for the localized stage is 93%.

  2. Regional: It is the second stage under which the cancer is found in two or more lymph nodes and spreads from one lymph node to another organ. The 5-year survival rate for the regional stage is 95%.

  3. Distant: Under this stage, the cancer has spread to different or distant parts of the body. These include the bone marrow, liver, lungs, or lymph nodes areas above and below the diaphragm. The 5-year survival rate for the distant stage is 83%.

Survival Rate for Non-Hodgkin Lymphoma

The survival rate for non-Hodgkin's lymphoma varies depending on the specific type and stage of the cancer. Advanced medical research and the development of targeted therapies have contributed to better outcomes. Moreover, this has improved survival rates for non-Hodgkin's lymphoma.

According to the American Cancer Society, the survival rates for different stages of non-Hodgkins lymphoma are as follows:

  1. Localised: This is the first stage of cancer under which the spread is limited to one lymphoid organ, one organ outside the lymph system, or one lymph node area. The 5-year survival rate for the localized stage is 73%.

  2. Regional: This is the second stage under which cancer reaches from one lymph node area to a nearby organ, spreads to two or more lymph node areas, or is considered a bulky disease. The 5-year survival rate for the regional stage is 74%.

  3. Distant: This is the third stage, where the cancer spreads to distant parts of the body. This includes the liver, lungs, bone marrow, or the area around the lymph nodes. The 5- year survival rate for the distant stage is 58%. 

Besides the stage, the survival rate for non-Hodgkin’s lymphoma can also differ based on the patient's age and the type of NHL. The survival rate as per age is as follows:

  1. Between 15 and 39: 82.4%

  2. Between 40 and 64: 78.5%

  3. Between 65 and 74: 72.1%

  4. 75 and above: 55.2%

The 5-year survival rates of the most common types of non-Hodgkin’s lymphoma include:

  1. Diffuse Large B-Cell Lymphoma is the most common aggressive type of NHL. The 5-year survival rate is 64%. 

  2. Follicular Lymphoma is a slow-growing type of lymphoma with an 89% survival rate. 

  3. Marginal Zone Lymphoma has different survival rates due to its slow-growing nature. The survival rates of its subtypes are:

    1. Mucosa-Associated Lymphoid Tissue: 88.7%

    2. Splenic Marginal Zone Lymphoma: 79.7%

    3. Nodal Marginal Zone Lymphoma: 76.5%

Factors Affecting Survival Rates

Several factors can influence the survival rates of Hodgkin's and Non-Hodgkin's lymphoma. Here are the key points:

  1. Stage at Diagnosis: The stage at which the cancer is diagnosed plays a critical role in determining the prognosis. Early detection allows for more effective treatment and higher chances of survival.

  2. Type of Lymphoma: There are different types of lymphomas, and each may have varying responses to treatment. Hodgkin's and Non-Hodgkin's lymphoma have distinct characteristics affecting their survival rates.

  3. Age and General Health: The age and overall health of the patient can impact the ability to tolerate treatments and recover from lymphoma. Younger and healthier individuals may have better survival rates.

  4. Biological Features: Specific biological features of lymphoma, such as genetic mutations, can influence its aggressiveness and response to treatment.

  5. Treatment Options: Advancements in treatment modalities, including chemotherapy, radiation therapy, immunotherapy, and targeted therapies, have significantly improved survival rates for both types of lymphoma.

  6. Patient Compliance: Adherence to the prescribed treatment plan and regular follow-up visits are essential for better outcomes and long-term survival.

Improving Survival Rates

Improving survival rates for Hodgkin's and non-Hodgkin's lymphoma involves early detection, accurate diagnosis, effective treatments, and supportive care. Below are the methods to improve the survival rates:

  1. Maintaining a healthy weight through a balanced diet and regular exercise.

  2. Diet rich in fruits, vegetables, whole grains, and lean proteins contains vital minerals and antioxidants that help the immune system.

  3. Regular medical check-ups and adherence to prescribed drugs and treatment programs are critical for disease management.

  4. Limiting your intake of processed foods, red meat, and sugary drinks may help reduce inflammation and encourage a better immune response.

Conclusion

Due to improvements in supportive care and treatment modalities, Hodgkin's and non-Hodgkin's lymphoma survival rates have dramatically increased in recent years. Early diagnosis and prompt commencement of suitable treatment significantly increase the likelihood of long-term survival. However, survival rates are statistical estimates that can change depending on several factors.

It is best to consult a doctor to understand the expectations from treatment. At HexaHealth, our experts are available round the clock to provide you with all the vital and accurate information. Schedule your appointment TODAY!

Suggested Reads

Leukaemia vs Lymphoma

Hodgkin Non-Hodgkin Lymphoma Treatment

Difference between Hodgkin and Non-Hodgkin Lymphoma

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Frequently Asked Questions

Hodgkin's lymphoma survival rates vary based on several variables, including the disease's stage, the patient's age, etc.

According to the American Cancer Society, the average five-year survival rate of Hodgkin's lymphoma is about 89%.

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Non-Hodgkin's lymphoma (NHL) survival rates vary based on several variables, including the precise type and stage of the lymphoma.

According to the American Cancer Society, the 5-year survival rate of non-Hodgkin's lymphoma is up to 70%.

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Most non-Hodgkin's lymphoma varieties have lower survival rates than Hodgkin's lymphoma does.

Particularly in its early stages, HL is regarded as a more treatable and frequently curable form of lymphoma. Hodgkin's lymphoma has an average five-year survival rate of about 80%.

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Here are some key factors that can impact the survival rate:

  1. Stage: The Hodgkin's lymphoma diagnosis stage substantially impacts the likelihood of survival. 

  2. Age: Older patients have a comparatively lower chance of surviving Hodgkin's lymphoma. Younger patients have a better propensity to survive than those who are older.\

  3. Gender: Research has indicated that females with Hodgkin's lymphoma typically have a better prognosis than males.

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factors that impact the survival rate for lymphoma are : 

  1. Gender: For certain types of lymphomas, the survival rate has been slightly compromised in adults compared to young people.

  2. Race: Factors such as race, ethnicity, genetic factors, etc., also significantly impact the survival rate.

  3. Socioeconomic Status: Patients with low or average socioeconomic status have limited availability of healthcare facilities and other treatment options. This, the result, is sure to compromise better chances of survival.

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 Yes, Hodgkin's lymphoma survival rates vary depending on the disease's stage.

The Hodgkin's lymphoma staging system, often known as the Ann Arbor staging system, divides the condition into I, II, III, and IV stages. 

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Yes, depending on the stage of the disease, non-Hodgkin's lymphoma (NHL) survival rates might vary.

The survival rate in the first stage is up to 81%, which can go down to 58% in the last stage.

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Hodgkin's lymphoma can vary depending on several variables, including the patient's unique traits and the treatment they received.

The 5-year survival rate for stage 4 Hodgkin's lymphoma can range from around 65% to 80%.

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The stage 4 non-Hodgkin's lymphoma survival rate might vary significantly based on the particular subtype and individual circumstances.

Stage 4 NHL has an estimated 5-year survival rate of 58.5 on average.

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Hodgkin's lymphoma survival rates have significantly increased over time. According to population-based statistics, Hodgkin's lymphoma patient survival rates have increased throughout all stages.

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Younger patients typically have higher survival rates than older patients. This variation can be ascribed to several variables, including general health and treatment tolerance.

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Yes, particular treatments have been demonstrated to increase lymphoma patients' chances of survival. The specific treatments include : 

  1. Chemotherapy 

  2. Bone marrow transplantation

  3. Radiotherapy 

  4. Immunotherapy 

  5. Targeted therapies 

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Yes, some long-term effects and complications can impact the survival rate of lymphoma survivors. These include: 

  1. Redvelopemnt of cancer 

  2. Infections 

  3. Thyroid problems 

  4. Heart disease & stroke 

  5. Fertility problems 

  6. Lung damage 

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On average, the 5-year and 10-year survival rates for Hodgkin lymphoma are 87% and 80%, respectively.

The 5-year and 10-year survival rates for non-Hodgkins lymphoma are 74% and 55%, respectively.

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Children and adults may have different lymphoma survival rates due to a variety of circumstances, such as : 

  1. Differences in disease biology

  2. Therapeutic regimens

  3. General health

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The overall prognosis for patients diagnosed with Hodgkin's lymphoma or non-Hodgkin's lymphoma can vary widely depending on several factors. The overall prognosis includes the following: 

  1. 89% of the patients with Hodgkin's lymphoma survive for five years or more.

  2. 74% of the patients diagnosed with non-Hodgkins lymphoma survive for five years or more.

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References

All the articles on HexaHealth are supported by verified medically-recognized sources such as; peer-reviewed academic research papers, research institutions, and medical journals. Our medical reviewers also check references of the articles to prioritize accuracy and relevance. Refer to our detailed editorial policy for more information.


  1. Hodgkin Lymphoma Survival Rates | Hodgkin Disease Survival Rates [Internet]. www.cancer.org. link
  2. Hodgkin’s vs. Non-Hodgkin’s Lymphoma: What’s the Difference? [Internet]. NFCR. 2019. link
  3. Hodgkin’s Lymphoma vs. Non-Hodgkin’s Lymphoma: Differences & More [Internet]. Healthline. 2021.link
  4. Bhurani D, Nair R, Rajappa S, Rao SA, Sridharan N, Boya RR, et al. Real-World Outcomes of Hodgkin Lymphoma: A Multi-Centric Registry From India. Frontiers in Oncology. 2022 Feb 11;11.link
  5. Non-Hodgkin’s Lymphoma: Life Expectancy, Quality of Life & More [Internet]. Healthline. 2022. link
  6. Survival Rates for Non-Hodgkin’s Lymphoma [Internet]. Healthline. 2021 [cited 2023 Aug 2]. link

Last Updated on: 11 August 2023

Disclaimer: The information provided here is for educational and learning purposes only. It doesn't cover every medical condition and might not be relevant to your personal situation. This information isn't medical advice, isn't meant for diagnosing any condition, and shouldn't replace talking to a certified medical or healthcare professional.

Reviewer

Dr. Aman Priya Khanna

Dr. Aman Priya Khanna

MBBS, DNB General Surgery, Fellowship in Minimal Access Surgery, FIAGES

12 Years Experience

Dr Aman Priya Khanna is a well-known General Surgeon, Proctologist and Bariatric Surgeon currently associated with HealthFort Clinic, Health First Multispecialty Clinic in Delhi. He has 12 years of experience in General Surgery and worke...View More

Author

Sangeeta Sharma

Sangeeta Sharma

BSc. Biochemistry I MSc. Biochemistry (Oxford College Bangalore)

6 Years Experience

She has extensive experience in content and regulatory writing with reputed organisations like Sun Pharmaceuticals and Innodata. Skilled in SEO and passionate about creating informative and engaging medical conten...View More

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